In vitro data demonstrates that APIS reduces bacterial load, decreases MMP-9, and triggers the release of growth factors, which has been shown to instill balance in the wound microenvironment and progress the wound toward healing.
GELATIN
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A natural protein matrix
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Beneficial for call migration, adhesion, and proliferation, essential for wound granulation and ephitheliazation
MANUKA HONEY
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Inhibits bacterial growth
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Anti-inflammatory effect via suppression of MMP activity and neutrophil recruitment
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Promotes healing by increasing fibroblast activity
HYDROXYAPATITE
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Binds proteins for cell attachment, proliferation, and differentiation
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Promotes wound healing via angiogenesis and re-ephitheliation
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Provides structural support to scaffolds
KEY FEATURES
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Shelf stable at room temperature
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Excellent biocompatibility
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Pyrogen free, non-cytotix, non-sentisizing, non-irritant, low endotoxins
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Ready to use within minutes
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Trimmable to fit a specific wound shape
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Omnidirectional (apply in any orientation)
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Naturally adheres to the wound upon contact, allowing for easy placement
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Conforms to the wound, maximizing contact
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Naturally absorbed by the body
INDICATIONS
Under the supervision of a healthcare professional, APIS is indicated for use in the management of wounds, including:
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Full and partial thickness wounds
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Pressure ulcers (stages I-IV)
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Venous stasis ulcers
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Diabetic ulcers
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Surface wounds
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Traumati wounds (healing by secondary intention)
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Surgical wounds
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Abrasions
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Donor site wounds
